Breast Cancer: Challenges, Breakthroughs

Breast cancer is the second most common cancer diagnosed after lung cancer and is the main cause of cancer demise in women. The heterogeneity of breast cancer such as ductal carcinoma in situ, triple negative breast cancer, HER2 negative among the women makes it difficult for the doctors to provide ideal medications for the cure. The major treatment methods are chemotherapy, radiation therapy, targeted drug therapy, oncoplastic surgery etc. Recent oncology research lead to the developments in neoadjuvant therapies, have also been benefited in treatment of breast cancer. Complete cure through Ayurveda was another major breakthrough in breast cancer treatment.

  • Mechanisms of resistance to therapies
  • Epigenetic alterations
  • Accelerated partial breast irradiation (APBI)
  • Single nucleotide polymorphism
  • Identification of genetic changes
  • Personalized anticancer therapy
  • Letrozole
  • Palbociclib and Ribociclib
  • BRCA proteins
  • Poly(ADP ribose) polymerase (PARP) inhibitors
  • Basal-like breast cancer
  • HER2-targeted therapies

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